RNA Biology
Welcome to RNA Biology, an undergraduate-level textbook on the biology, chemistry, and technology of RNA.
RNA sits at the center of the central dogma of molecular biology. It is the cell’s most dynamic controller: it stores and transmits information, folds into functional structures, catalyzes reactions, guides molecular recognition, regulates gene expression, and powers a growing family of medicines and technologies.
This book covers RNA comprehensively across its 28 parts: chemistry, structure and biophysics, synthesis, processing, turnover, translation, and regulatory RNAs, as well as computational algorithms and AI, measurement technologies, virology, and medicine, from therapeutics and delivery to synthetic biology.
About This Book
The complete architecture spans 165 chapters organized into 28 parts.
This book was written by Hyeshik Chang using ChatGPT (Parts 1–25, except Part 19) and DeepSeek (Part 19, which covers the virology sections). He set the editorial direction, built the writing, editing, and reviewing workflows, and reviewed the content. Review and editing are ongoing, and the text is continually refined to reflect the scientific consensus of contemporary research communities.
The content is also intended to serve as a knowledge base for AI-agent queries. For the original AI-friendly source formats, see the book’s GitLab repository.
165 of 165 chapters are currently available. See the table of contents in the sidebar to start reading.
This book is rendered on the chaek platform from Markdown sources.